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#autophagic

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The EMBO Journal<p>Why is functional <a href="https://sciencemastodon.com/tags/autophagy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagy</span></a> important for <a href="https://sciencemastodon.com/tags/cardiac" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cardiac</span></a> health?<br>Abel Lab and collaborators shows that <a href="https://sciencemastodon.com/tags/autophagic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagic</span></a> flux controls NAD+ homeostasis in <a href="https://sciencemastodon.com/tags/cardiomyocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cardiomyocytes</span></a>, thereby preventing <a href="https://sciencemastodon.com/tags/mitochondrial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mitochondrial</span></a> dysfunction<br><a href="https://www.embopress.org/doi/full/10.1038/s44318-023-00009-w" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/full/10.1038</span><span class="invisible">/s44318-023-00009-w</span></a></p>
The EMBO Journal<p>TFEB-dependent lysosome biogenesis is required for <a href="https://sciencemastodon.com/tags/senescence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>senescence</span></a><br>by Bernadette Carroll and coworkers</p><p>Transcription factor <a href="https://sciencemastodon.com/tags/TFEB" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TFEB</span></a> induces <a href="https://sciencemastodon.com/tags/lysosome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>lysosome</span></a> proliferation in <a href="https://sciencemastodon.com/tags/senescent" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>senescent</span></a> cells, counterbalancing reduced lysosomal efficiency and maintaining <a href="https://sciencemastodon.com/tags/autophagic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagic</span></a> capacity<br><a href="https://www.embopress.org/doi/10.15252/embj.2022111241" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/10.15252/emb</span><span class="invisible">j.2022111241</span></a></p>
The EMBO Journal<p>A <a href="https://sciencemastodon.com/tags/protelysis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>protelysis</span></a> cascade fine-tunes homologous <a href="https://sciencemastodon.com/tags/recombination" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>recombination</span></a> repair in plants:<br>Arp Schnittger and coworkers show <a href="https://sciencemastodon.com/tags/KNOTEN1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>KNOTEN1</span></a>, stabilized by <a href="https://sciencemastodon.com/tags/UBP12" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>UBP12</span></a>/13, triggering K63-linked <a href="https://sciencemastodon.com/tags/ubiquitination" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ubiquitination</span></a> and <a href="https://sciencemastodon.com/tags/autophagic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>autophagic</span></a> degradation of <a href="https://sciencemastodon.com/tags/BLM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BLM</span></a> complex subunit <a href="https://sciencemastodon.com/tags/RMI1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RMI1</span></a> upon <a href="https://sciencemastodon.com/tags/DNAdamage" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DNAdamage</span></a></p><p><a href="https://www.embopress.org/doi/10.15252/embj.2022111980" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/10.15252/emb</span><span class="invisible">j.2022111980</span></a></p>
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